Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.49 |
| ▸ | CES1 | P23141 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25704232 | 0.91 | MALT1 (0.47) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL3331799 | 0.89 | MALT1 (0.56) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8186444 | 0.74 | MALT1 (0.76) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8023976 | 0.74 | MALT1 (0.55) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL15034364 | 0.69 | MALT1 (0.76) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL25704068 | 0.69 | MALT1 (0.59) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL5940394 | 0.67 | MALT1 (0.74) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| Lapachone SCHEMBL107042 | 0.67 | MALT1 (1.00) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| Lapachone SCHEMBL29351050 | 0.67 | MALT1 (1.00) | MALT1CES1KDM4EMEN1ALDH1A1 | |
| SCHEMBL5940435 | 0.66 | MALT1 (0.75) | MALT1CES1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008066296-A1 | PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |