Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.76 |
| ▸ | IDO1 | P14902 | 7/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | CES2 | O00748 | 1/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | TDP2 | O95551 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | NQO1 | P15559 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15034364 | 0.88 | MALT1 (0.76) | MALT1IDO1LMNAKDM4EMEN1 | |
| Lapachone SCHEMBL107042 | 0.86 | MALT1 (1.00) | MALT1IDO1LMNAKDM4EMEN1 | |
| Lapachone SCHEMBL29351050 | 0.86 | MALT1 (1.00) | MALT1IDO1LMNAKDM4EMEN1 | |
| SCHEMBL8260300 | 0.85 | MALT1 (0.54) | MALT1IDO1LMNAKDM4EMEN1 | |
| Alpha-Lapachone SCHEMBL102553 | 0.81 | IDO1 (1.00) | MALT1IDO1LMNAKDM4EMEN1 | |
| Alpha-Lapachone SCHEMBL29355317 | 0.81 | IDO1 (1.00) | MALT1IDO1LMNAKDM4EMEN1 | |
| SCHEMBL8260327 | 0.81 | MALT1 (0.50) | MALT1IDO1LMNAKDM4EMEN1 | |
| SCHEMBL10916022 | 0.80 | MALT1 (0.72) | MALT1IDO1LMNAKDM4EMEN1 | |
| SCHEMBL10916020 | 0.80 | MALT1 (0.72) | MALT1IDO1LMNAKDM4EMEN1 | |
| SCHEMBL8023976 | 0.79 | MALT1 (0.55) | MALT1IDO1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532389-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532388-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |