Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347229 | 0.84 | CYP2D6 (0.54) | CYP2D6KLF10TSHRMAOBCYP2C19 | |
| SCHEMBL9701313 | 0.82 | CYP2D6 (0.35) | CYP2D6MAOBCYP2C19CYP1A2KIF11 | |
| SCHEMBL8849619 | 0.82 | CYP2D6 (0.38) | CYP2D6TSHRMAOBCYP2C19CYP1A2 | |
| SCHEMBL9347249 | 0.81 | CYP2D6 (0.37) | CYP2D6TSHRMAOBRAB9AALDH1A1 | |
| SCHEMBL7499812 | 0.79 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL7498972 | 0.78 | CYP2D6 (0.32) | CYP2D6TSHR | |
| SCHEMBL7505966 | 0.78 | ADRB2 (0.34) | CYP2D6MAOBCYP2C19RAB9A | |
| SCHEMBL9343298 | 0.77 | CYP2C19 (0.54) | CYP2C19RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL7488075 | 0.77 | CYP2D6 (0.38) | CYP2D6TSHRRXRARXRB | |
| SCHEMBL9472706 | 0.76 | CYP2D6 (0.33) | CYP2D6RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739349-B1 | POLYMER-SUPPORTED SOLUTION SYNTHESIS OF OLIGOSACCHARIDES | INNOVATIONS FOUNDATION (CA) | 2000-05-17 | — | — | EP | disclosed |
| US-5616698-A | Polymer-supported solution synthesis of oligosaccharides | UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) | 1997-04-01 | — | — | US | disclosed |
| EP-0739349-A1 | POLYMER-SUPPORTED SOLUTION SYNTHESIS OF OLIGOSACCHARIDES | INNOVATIONS FOUNDATION (CA) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018814-A2 | POLYMER-SUPPORTED SOLUTION SYNTHESIS OF OLIGOSACCHARIDES | INNOVATIONS FOUNDATION (CA) | 1995-07-13 | — | — | WO | disclosed |