Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.67 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795584 | 0.86 | PDE4B (0.67) | PDE4BPDE4DCNR2PGK1MAPT | |
| SCHEMBL27595204 | 0.81 | PDE4B (0.60) | PDE4BPDE4DCNR2PGK1MAPT | |
| SCHEMBL8062503 | 0.80 | PDE4B (0.65) | PDE4BPDE4DSMN1; SMN2CTSA | |
| SCHEMBL3787844 | 0.80 | PDE4B (0.59) | PDE4BPDE4DCNR2PGK1MAPT | |
| SCHEMBL3790133 | 0.76 | PDE4B (0.67) | PDE4BPDE4D | |
| SCHEMBL14151596 | 0.74 | CNR2 (0.60) | PDE4BPDE4DCNR2CTSA | |
| SCHEMBL16044163 | 0.74 | PDE4B (0.63) | PDE4BPDE4DCNR2CTSA | |
| SCHEMBL4316685 | 0.73 | PDE4D (0.70) | PDE4BPDE4DCNR2CTSA | |
| SCHEMBL15674640 | 0.72 | PDE4B (0.53) | PDE4BPDE4DCNR2PGK1MAPT | |
| SCHEMBL8069736 | 0.71 | PDE4B (0.60) | PDE4BPDE4DCNR2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |