Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705329 | 0.95 | TERT (0.61) | TERTRXFP1MAPTPDE5ASMN1; SMN2 | |
| SCHEMBL8066739 | 0.92 | TERT (0.45) | TERTRXFP1MAPTHSD17B10S1PR3 | |
| SCHEMBL8125815 | 0.89 | TERT (0.62) | TERTRXFP1MAPTHSD17B10PDE5A | |
| SCHEMBL8056309 | 0.88 | TERT (0.50) | TERTRXFP1MAPTHSD17B10PDE5A | |
| SCHEMBL13662764 | 0.87 | TERT (0.47) | TERTRXFP1MAPTHSD17B10S1PR3 | |
| SCHEMBL8055429 | 0.85 | TERT (0.56) | TERTRXFP1MAPTHDAC1HDAC6 | |
| SCHEMBL8055436 | 0.82 | PDE5A (0.56) | TERTMAPTPDE5A | |
| SCHEMBL6284529 | 0.81 | TERT (0.53) | TERTRXFP1HTTRAB9A | |
| SCHEMBL13990468 | 0.80 | TERT (0.53) | TERTRXFP1PDE5APDE4DSMN1; SMN2 | |
| SCHEMBL4741016 | 0.78 | PDE5A (0.58) | TERTMAPTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194529-A1 | HIGHLY SELECTIVE and LONG-ACTING PDE5 MODULATORS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194529-A1 | HIGHLY SELECTIVE and LONG-ACTING PDE5 MODULATORS | PDE5A, PDE7A, PDE3A | TERT 3651/4885RXFP1 682/4885MAPT 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.