Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411987 | 0.82 | HSD17B10 (0.61) | GABRA5GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL8055620 | 0.81 | HDAC1 (0.37) | GABRA5GABRB2HSD17B10 | |
| SCHEMBL8056581 | 0.81 | MEN1 (0.39) | GABRA5GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL2895259 | 0.78 | GABRA5 (0.47) | GABRA5GABRB2HSD17B10CSNK2A1ALDH1A1 | |
| SCHEMBL1797901 | 0.78 | GABRA5 (0.72) | GABRA5GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL10431345 | 0.77 | GABRA5 (0.46) | GABRA5GABRB2HSD17B10CSNK2A1ALDH1A1 | |
| SCHEMBL2745279 | 0.77 | GABRA5 (0.46) | GABRA5GABRB2HSD17B10CSNK2A1ALDH1A1 | |
| SCHEMBL5544014 | 0.77 | SMN1; SMN2 (0.57) | GABRA5GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL7746931 | 0.77 | KDM4E (0.40) | GABRA5GABRB2HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8055597 | 0.77 | MEN1 (0.44) | GABRA5GABRB2HSD17B10ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150351-A | ADMINISTERING AN EFFECTIVE AMOUNT OF THE CEPHEM COMPOUND TO A PATIENT SUFFERING FROM DISEASES CAUSED BY HELICOBACTER PYLORI | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0882052-A1 | NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997029111-A1 | NEW CEPHEM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-14 | — | — | WO | disclosed |