Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855747 | 0.96 | KDM4E (0.47) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL10458612 | 0.81 | KDM4E (0.55) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL8611143 | 0.81 | KDM4E (0.55) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL31125348 | 0.78 | KDM4E (0.48) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL8048915 | 0.77 | SMN1; SMN2 (0.46) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL8051194 | 0.77 | HTT (0.53) | HTTSMN1; SMN2NPC1RAB9AALOX12 | |
| SCHEMBL9316629 | 0.75 | KDM4E (0.49) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL26343359 | 0.75 | KDM4E (0.49) | LMNAHTTSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL14855424 | 0.75 | TSHR (0.48) | LMNAHTTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL19404527 | 0.74 | TP53 (0.58) | LMNAKDM4EOPRK1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083961-A | FOR PREVENTION AND/OR TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | claimed |