Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055397 | 0.83 | KMT2A (0.45) | PABPC1EIF4HCTDSP1KMT2AMEN1 | |
| SCHEMBL19968566 | 0.81 | MEN1 (0.45) | PABPC1EIF4HCTDSP1KMT2AMEN1 | |
| SCHEMBL30218182 | 0.79 | MEN1 (0.44) | PABPC1EIF4HCTDSP1KMT2AMEN1 | |
| SCHEMBL351087 | 0.79 | BCHE (0.52) | ACHE | |
| SCHEMBL918101 | 0.79 | PABPC1 (0.47) | PABPC1EIF4HCTDSP1KMT2AMEN1 | |
| SCHEMBL3072750 | 0.78 | HTT (0.50) | PABPC1EIF4HCTDSP1ALDH1A1CYP2C19 | |
| Sulfuric Acid SCHEMBL28430151 | 0.77 | BCHE (0.50) | ACHE | |
| Water SCHEMBL1254758 | 0.77 | BCHE (0.50) | ACHE | |
| SCHEMBL28671146 | 0.76 | PABPC1 (0.38) | PABPC1EIF4HCTDSP1KMT2AMEN1 | |
| Water SCHEMBL1047262 | 0.76 | HTT (0.48) | PABPC1EIF4HCTDSP1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060206-A1 | 3,4,6,7-TETRAHYDRO-1H-PYRROLO[3,4-D]PYRIMIDINE-2,5-DIONES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |