Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724312 | 0.88 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6721564 | 0.86 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL806536 | 0.86 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL8055955 | 0.86 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL21561303 | 0.85 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL21561261 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL5715568 | 0.84 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL8655413 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8974230 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL9464193 | 0.82 | CYP17A1 (0.61) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794942-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-31 | — | — | EP | claimed |