Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066936 | 0.98 | PTGIR (0.59) | PTGIRFABP4KDM4ECYP3A4HPGD | |
| SCHEMBL9006890 | 0.87 | PTGIR (0.51) | PTGIRKDM4ECYP3A4HPGDALDH1A1 | |
| SCHEMBL9006887 | 0.86 | PTGIR (0.49) | PTGIRKDM4ECYP3A4HPGDPTGER4 | |
| SCHEMBL9006922 | 0.85 | PTGIR (0.51) | PTGIRKDM4ECYP3A4HPGDALDH1A1 | |
| SCHEMBL8055942 | 0.85 | PTGIR (0.66) | PTGIRFABP4KDM4ECYP3A4HPGD | |
| SCHEMBL9006917 | 0.84 | PTGIR (0.49) | PTGIRKDM4ECYP3A4HPGDPTGER4 | |
| SCHEMBL27337328 | 0.83 | PTGIR (0.46) | PTGIRKDM4ECYP3A4HPGDTBXA2R | |
| SCHEMBL8056487 | 0.82 | PTGIR (0.85) | PTGIRFABP4KDM4ECYP3A4HPGD | |
| SCHEMBL8055541 | 0.81 | FABP4 (0.58) | PTGIRFABP4KDM4ECYP3A4HPGD | |
| SCHEMBL27408640 | 0.81 | PTGIR (0.46) | PTGIRKDM4ECYP3A4HPGDTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-B1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-6025375-A | INHIBITORY ACTIVITY ON PLATELET AGGREGATION, VASODILATING ACTIVITY, ANTIHYPERTENSIVE ACTIVITY OR THE LIKE AND ARE PROSTAGLANDIN I.SUB.2 AGONISTS, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| WO-1995017393-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-29 | — | — | WO | disclosed |