Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.58 |
| ▸ | MME | P08473 | 7/20 | 0.58 |
| ▸ | XIAP | P98170 | 3/20 | 0.56 |
| ▸ | CCKBR | P32239 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200771 | 0.91 | XIAP (0.56) | ACEMMEXIAP | |
| SCHEMBL8050289 | 0.89 | ACE (0.70) | ACEMMECCKBR | |
| SCHEMBL7359930 | 0.87 | ACE (0.59) | ACEMMECCKBR | |
| SCHEMBL7356075 | 0.83 | F2 (0.54) | ACEMME | |
| SCHEMBL7353391 | 0.81 | ACE (0.52) | ACEMMECCKBR | |
| SCHEMBL7420611 | 0.80 | ACE (0.46) | ACEMME | |
| SCHEMBL10200768 | 0.80 | ACE (0.67) | ACEMMECCKBR | |
| SCHEMBL2222575 | 0.78 | OPRL1 (0.50) | ACEMMECCKBR | |
| SCHEMBL7356369 | 0.78 | OPRL1 (0.50) | ACEMMECCKBR | |
| SCHEMBL8056271 | 0.78 | ACE (0.74) | ACEMMECCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994894-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007731-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |