2,4-Dichlorophenol

2,4-Dichlorophenol

SCHEMBL8056359

Oc1ccc(Cl)cc1.Oc1ccc(Cl)cc1Cl

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.81
TSHR P16473 3/20 0.81
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 1/20 0.52
ESR2 Q92731 2/20 0.48
ESR1 P03372 1/20 0.48
HPGD P15428 5/20 0.48
ALOX15 P16050 3/20 0.48
ALOX12 P18054 2/20 0.48
MAPK1 P28482 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
HSP90AA1 P07900 3/20 0.46
MEN1 O00255 2/20 0.46
HTT P42858 2/20 0.46
KMT2A Q03164 2/20 0.46
HIF1A Q16665 2/20 0.46
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenol SCHEMBL77936 0.90
2,4-Dichlorophenol SCHEMBL30084868 0.90
2,4-Dichlorophenol SCHEMBL30396784 0.90
2,4-Dichlorophenol SCHEMBL28226615 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL29404519 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL28226476 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL7394579 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL8526331 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL28227287 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1
2,4-Dichlorophenol SCHEMBL27937117 0.87 HSD17B10 (0.94) HSD17B10TSHRALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4410715-A Process for the epoxidation of olefins using a group V metal co-catalyst I and a phenolic hydrocarbon co-catalyst II EXXON RESEARCH & ENGINEERING CO. (US) 1983-10-18 US claimed
EP-0516948-B1 Chemiluminescent method and compositions LUMIGEN INC (US) 2000-05-31 EP disclosed
US-5877389-A Process for the oxidative decomposition of organic compounds present in aqueous effluents ELF AQUITAINE (FR) 1999-03-02 US disclosed