2,4-Dichlorophenol

2,4-Dichlorophenol

SCHEMBL8526331

Oc1ccc(Cl)cc1Cl.[Na]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.94
TSHR P16473 6/20 0.94
CYP3A4 P08684 6/20 0.59
ALDH1A1 P00352 5/20 0.59
TDP1 Q9NUW8 1/20 0.59
HPGD P15428 6/20 0.54
ALOX15 P16050 3/20 0.54
ALOX12 P18054 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
MAPK1 P28482 1/20 0.54
TP53 P04637 1/20 0.52
HSP90AA1 P07900 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
MEN1 O00255 2/20 0.52
HTT P42858 2/20 0.52
KMT2A Q03164 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenol SCHEMBL29404519 1.00 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL30084868 0.97
2,4-Dichlorophenol SCHEMBL77936 0.97
2,4-Dichlorophenol SCHEMBL30396784 0.97
2,4-Dichlorophenol SCHEMBL7394579 0.94 HSD17B10 (0.94) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL11506177 0.92 HSD17B10 (0.90) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL11041487 0.90 HSD17B10 (0.85) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL29034222 0.90 HSD17B10 (0.85) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL10988186 0.89 HSD17B10 (0.74) HSD17B10TSHRCYP3A4ALDH1A1TDP1
2,4-Dichlorophenol SCHEMBL8056359 0.87 HSD17B10 (0.81) HSD17B10TSHRCYP3A4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130337481-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2013-12-19 US claimed
EP-2656082-A1 ASSAY METHOD Reactivlab Limited (GB) 2013-10-30 EP claimed
WO-2012085497-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2012-06-28 WO claimed
CN-112608976-B Detection kit and detection method for periodontal pathogen infection marker 珠海市德灏生物科技有限公司 2023-03-17 CN disclosed
CN-112608976-A Detection kit and detection method for periodontal pathogen infection marker 珠海市德灏生物科技有限公司 2021-04-06 CN disclosed
US-20130337481-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2013-12-19 US disclosed
EP-2656082-A1 ASSAY METHOD Reactivlab Limited (GB) 2013-10-30 EP disclosed
WO-2012085497-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2012-06-28 WO disclosed
EP-0885970-A1 METHOD FOR ASSAYING AMMONIA AND COMPOSITION THEREFOR Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-12-23 EP disclosed
US-4826761-A FOR COLORIMETRIC ANALYSIS FUJI PHOTO FILM CO, LTD. (JP) 1989-05-02 US disclosed
EP-0205844-A1 Diagnostic method for detecting periodontal disease Richardson-Vicks, Inc. (US) 1986-12-30 EP disclosed