Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925327 | 0.85 | PTGS2 (0.69) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8053369 | 0.85 | PTGS2 (0.69) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL6288814 | 0.79 | PTGS2 (0.62) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL9026538 | 0.78 | PTGS2 (0.73) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL9026535 | 0.78 | PTGS2 (0.73) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14823468 | 0.77 | HPGD (0.85) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL7217583 | 0.77 | CYP2A6 (0.47) | PTGS2ALDH1A1KDM4EESR1ESR2 | |
| SCHEMBL7217591 | 0.77 | CYP2A6 (0.47) | PTGS2ALDH1A1KDM4EESR1ESR2 | |
| SCHEMBL10325004 | 0.77 | PTGS2 (0.50) | PTGS2ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL10325003 | 0.77 | PTGS2 (0.50) | PTGS2ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093864-A | Aromatic dimethylidyne compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0388768-B1 | Organic electroluminescent device containing aromatic dimethylidyne compounds | IDEMITSU KOSAN CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0616020-A1 | Aromatic dimethylidyne compounds and process for preparation thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5130603-A | A stilbene, bluish purple to green | IDEMITSU KOSAN CO., LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0388768-A2 | Organic electroluminescent device containing aromatic dimethylidyne compounds | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |