SCHEMBL80565

SCHEMBL80565

Clc1ccc(I)cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30469268 1.00
SCHEMBL26302780 0.79
SCHEMBL1350393 0.79
SCHEMBL6269096 0.79 IDO1 (0.43)
SCHEMBL1932575 0.75
SCHEMBL545042 0.75
SCHEMBL979907 0.75
SCHEMBL1118567 0.75
SCHEMBL219910 0.75
SCHEMBL79161 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111097520-A Covalent organic framework material loaded Pd catalyst and preparation method and application thereof 中国科学院广州能源研究所 2020-05-05 CN claimed
US-20260008782-A1 HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION CONVELO THERAPEUTICS, INC. 2026-01-08 US disclosed
US-12358869-B2 Diarylureas as CB1 allosteric modulators RESEARCH TRIANGLE INSTITUTE 2025-07-15 US disclosed
US-20250115576-A1 THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2025-04-10 US disclosed
WO-2025049767-A1 AMIDE PRODRUGS AND USES THEREOF AUTOBAHN THERAPEUTICS, INC. (US) 2025-03-06 WO disclosed
US-12209075-B2 Pyridine-sulfonamide derivatives as sodium channel inhibitors GENENTECH, INC. (US) 2025-01-28 US disclosed
US-20240270705-A1 COMPOUNDS SELECTIVE FOR JAK1 AND METHODS OF USE VIVIDION THERAPEUTICS, INC. 2024-08-15 US disclosed
CN-111902403-B Substituted alkynylene compounds as anticancer agents 奥里吉恩发现科技有限公司 2024-05-17 CN disclosed
WO-2024088109-A1 ARYL HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 复旦大学 2024-05-02 WO disclosed
WO-2024073658-A1 HYDANTOIN MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION GENENTECH, INC. (US) 2024-04-04 WO disclosed
US-4861880-A 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents PFIZER INC. (US) 1989-08-29 US disclosed
US-4743703-A Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1988-05-10 US disclosed
EP-0104860-B1 1-PHENYL-2(1H,3H)-INDOLONE PSYCHO-THERAPEUTIC AGENTS PFIZER INC. (US) 1987-03-18 EP disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
US-4476307-A Heteroylidene indolone compounds PFIZER INC. (US) 1984-10-09 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed
EP-0104860-A1 1-Phenyl-2(1H,3H)-indolone psycho-therapeutic agents PFIZER INC. (US) 1984-04-04 EP disclosed
US-4186153-A Process for 1,2,4,5-tetrachlorobenzene THE DOW CHEMICAL COMPANY (US) 1980-01-29 US disclosed
US-4158674-A Process for displacing nuclear iodine from substituted benzenes with chlorine THE DOW CHEMICAL COMPANY (US) 1979-06-19 US disclosed