SCHEMBL219910

SCHEMBL219910

Nc1ccc(I)cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277612 0.97 TSHR (0.54)
Benzenethiol SCHEMBL8153349 0.84 TSHR (0.42)
SCHEMBL1932575 0.79
SCHEMBL11826792 0.78 CYP3A4 (0.50)
SCHEMBL80565 0.75
SCHEMBL29674842 0.75
SCHEMBL30469268 0.75
SCHEMBL571047 0.75
SCHEMBL8872306 0.72 CYP3A4 (0.94)
SCHEMBL158279 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
CN-1213997-C Method for making 2-(N-phenylamino) benzoic acids WARNER LAMBERT CO (US) 2005-08-10 CN claimed
EP-1171418-B1 METHOD FOR MAKING 2-(N-PHENYLAMINO)BENZOIC ACIDS WARNER LAMBERT CO (US) 2004-12-29 EP claimed
US-6686499-B1 BY REACTING THE BENZOIC ACID IS 2,3,4,-TRIFLUOROBENZOIC ACID AND THE ANILINE 2-CHLORO-4-IODOANILINE IN LITHIUM HEXAMETHYLDISILAZIDE WARNER-LAMBERT COMPANY 2004-02-03 US claimed
CN-1347403-A Process for preparing 2- (N-phenylamino) benzoic acids WARNER LAMBERT CO (US) 2002-05-01 CN claimed
EP-1171418-A1 METHOD FOR MAKING 2-(N-PHENYLAMINO)BENZOIC ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-16 EP claimed
WO-2000064856-A1 METHOD FOR MAKING 2-(N-PHENYLAMINO)BENZOIC ACIDS WARNER-LAMBERT COMPANY (US) 2000-11-02 WO claimed
US-6362369-B1 None US disclosed
EP-4725941-A1 ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-15 EP disclosed
EP-4713327-A1 SPIRO DERIVATIVES AS WRN INHIBITORS Insilico Medicine IP Limited (HK) 2026-03-25 EP disclosed
EP-4313981-B1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS PFIZER (US) 2026-02-25 EP disclosed
US-20250263411-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS PFIZER INC. (US) 2025-08-21 US disclosed
US-5258399-A 5-lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-02 US disclosed
US-5236948-A Lipoxygenase inhibitor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-08-17 US disclosed
CN-1073674-A Sterilant ROUSSEL UCLAF (FR) 1993-06-30 CN disclosed
US-5208259-A Lipoxygenase enzyme inhibitors IMPERIAL CHEMICAL INDUSTRIES (GB) 1993-05-04 US disclosed
EP-0495594-A1 Sulphonamide derivatives ZENECA LIMITED (GB) 1992-07-22 EP disclosed
EP-0409413-A2 Diaryl ether heterocycles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-23 EP disclosed