⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129202 | 0.76 | — | — | |
| SCHEMBL71297 | 0.74 | — | — | |
| SCHEMBL455076 | 0.73 | — | — | |
| SCHEMBL18036 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL448776 | 0.73 | — | — | |
| SCHEMBL18990 | 0.73 | PRKCZ (0.37) | — | |
| SCHEMBL3835810 | 0.70 | — | — | |
| SCHEMBL3834527 | 0.70 | — | — | |
| SCHEMBL70257 | 0.69 | — | — | |
| SCHEMBL559813 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2085 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365620-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-11-16 | — | — | US | claimed |
| US-20230201200-A1 | Methods for Treating Huntington’s Disease | PTC THERAPEUTICS INC (US) | 2023-06-29 | — | — | US | claimed |
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | claimed |
| US-11072582-B2 | Substituted pyrrolidines as G-protein coupled receptor 43 agonists | EPICS THERAPEUTICS (BE) | 2021-07-27 | — | — | US | claimed |
| US-20210054020-A1 | CYCLIN-DEPENDENT KINASE DEGRADERS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-02-25 | — | — | US | claimed |
| EP-3154941-B1 | SMALL MOLECULE LFA-1 INHIBITORS | ALLOCYTE PHARMACEUTICALS AG (CH) | 2021-01-20 | — | — | EP | claimed |
| EP-3752518-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS AND METHODS OF USE | Dana Farber Cancer Institute, Inc. (US) | 2020-12-23 | — | — | EP | claimed |
| US-20200369715-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-26 | — | — | US | claimed |
| US-20200347016-A1 | SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS | EPICS THERAPEUTICS (BE) | 2020-11-05 | — | — | US | claimed |
| EP-3610872-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | EPICS THERAPEUTICS (BE) | 2020-02-19 | — | — | EP | claimed |
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | claimed |
| EP-0385662-B1 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-13 | — | — | EP | claimed |
| EP-0385663-B1 | Heterocyclic cycloalkanes as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-06 | — | — | EP | claimed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | claimed |
| EP-0420511-B1 | Heterocyclic derivatives | ICI PLC (GB) | 1994-08-17 | — | — | EP | claimed |
| EP-0381375-B1 | HETEROCYCLIC DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-11 | — | — | EP | claimed |
| EP-0420511-A2 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-03 | — | — | EP | claimed |
| EP-0385663-A2 | Heterocyclic cycloalkanes as inhibitors of 5-lipoxygenase | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | claimed |
| EP-0385662-A2 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | claimed |
| EP-0381375-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-08 | — | — | EP | claimed |