Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056816 | 0.87 | PDK1 (0.48) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29478907 | 0.82 | PDK1 (0.47) | SMN1; SMN2NPC1RAB9AHTTPDK1 | |
| SCHEMBL27096547 | 0.82 | PDK1 (0.47) | SMN1; SMN2NPC1RAB9AHTTPDK1 | |
| SCHEMBL29479086 | 0.82 | PDK1 (0.47) | SMN1; SMN2NPC1RAB9AHTTPDK1 | |
| SCHEMBL30121349 | 0.81 | MEN1 (0.54) | SMN1; SMN2NPC1RAB9AHTTTACR1 | |
| SCHEMBL24145841 | 0.80 | NAMPT (0.48) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL22234348 | 0.80 | NAMPT (0.48) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL22234269 | 0.80 | NAMPT (0.48) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1842426 | 0.79 | MEN1 (0.61) | SMN1; SMN2NPC1RAB9AHTTGPR119 | |
| SCHEMBL2796441 | 0.79 | MEN1 (0.48) | NAMPTSMN1; SMN2NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061076-A1 | N-ACYL CYCLIC AMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-6140333-A | FOR TREATMENT AND/OR PROPHYLAXIS OF DISEASES INCLUDE SUCH RESPIRATORY DISEASES AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES, CHRONIC BRONCHITIS, ASTHMA, CHRONIC RESPIRATORY OBSTRUCTION, PULMONARY FIBROSIS, PULMONARY EMPHYSEMA | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-10-31 | — | — | US | disclosed |