Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.56 |
| ▸ | CDC25B | P30305 | 5/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 5/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110122 | 0.90 | KDM1A (0.76) | KDM1AMEN1KMT2ALMNAPTPN1 | |
| SCHEMBL8056880 | 0.84 | PTPN1 (0.67) | KDM1AMEN1KMT2APTPN1CDC25B | |
| SCHEMBL25351420 | 0.82 | KMT2A (0.67) | KDM1AMEN1KMT2ALMNAPTPN1 | |
| SCHEMBL9615924 | 0.81 | KDM1A (0.58) | KDM1AMEN1KMT2APTPN1CDC25B | |
| SCHEMBL25352951 | 0.80 | KMT2A (0.65) | KDM1AMEN1KMT2ALMNAALOX12 | |
| SCHEMBL18230287 | 0.79 | KDM1A (0.50) | KDM1AMEN1KMT2ALMNAALOX12 | |
| SCHEMBL2762656 | 0.79 | DHODH (0.71) | MEN1KMT2ALMNAHTT | |
| SCHEMBL4115163 | 0.77 | HSD17B10 (0.68) | KDM1AMEN1KMT2APTPN1CDC25B | |
| SCHEMBL8056872 | 0.77 | KDM1A (0.58) | KDM1AMEN1KMT2APTPN1CDC25B | |
| SCHEMBL2781852 | 0.76 | KMT2A (0.70) | KDM1AMEN1KMT2ALMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | claimed |
| EP-0592664-B1 | DERIVATIVES OF DIPHENYLTHIAZOLE WITH ANTIINFLAMMATORY ACTIVITY | HISAMITSU PHARMACEUTICAL CO (JP) | 2000-07-05 | — | — | EP | disclosed |