Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.58 |
| ▸ | CDC25B | P30305 | 11/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 11/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066360 | 0.92 | CDC25B (0.59) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8056899 | 0.89 | PTPN1 (0.54) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8066039 | 0.88 | CDC25B (0.53) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8056502 | 0.86 | MAPT (0.61) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8067396 | 0.86 | MAPT (0.61) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8060240 | 0.84 | PTPN1 (0.64) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8072543 | 0.83 | PTGS2 (0.51) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8056906 | 0.81 | KDM1A (0.76) | KDM1ACDC25BDUSP3PTPN1PTGS2 | |
| SCHEMBL8067403 | 0.80 | MAPT (0.60) | CDC25BDUSP3PTPN1PTGS2ACHE | |
| SCHEMBL4115163 | 0.74 | HSD17B10 (0.68) | KDM1ACDC25BDUSP3PTPN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4173782-A | — | — | None | — | — | JP | disclosed |
| JP-H04173782-A | 2-SULFONAMIDE-4,5-DIPHENYLTHIAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1992-06-22 | — | — | JP | disclosed |