Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608096 | 0.89 | — | — | |
| SCHEMBL12606765 | 0.87 | — | — | |
| SCHEMBL12608016 | 0.87 | — | — | |
| SCHEMBL12608010 | 0.86 | GAA (0.31) | — | |
| SCHEMBL16349821 | 0.86 | GAA (0.31) | BACE1 | |
| SCHEMBL13685751 | 0.85 | F2 (0.32) | BACE1 | |
| SCHEMBL13685100 | 0.83 | F2 (0.33) | BACE1 | |
| SCHEMBL8290545 | 0.82 | CTSD (0.33) | BACE1 | |
| SCHEMBL12856082 | 0.82 | CTSD (0.33) | BACE1 | |
| SCHEMBL8290536 | 0.82 | GAA (0.33) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058856-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |