SCHEMBL80570

SCHEMBL80570

O=C(O)/C=C/c1ccc(C(F)(F)F)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.75
HDAC3 O15379 2/20 0.68
HDAC1 Q13547 2/20 0.68
HDAC2 Q92769 2/20 0.68
HDAC10 Q969S8 2/20 0.68
HDAC11 Q96DB2 2/20 0.68
HDAC8 Q9BY41 2/20 0.68
HDAC6 Q9UBN7 2/20 0.68
HDAC5 Q9UQL6 2/20 0.68
ADAM17 P78536 1/20 0.68
MAOB P27338 6/20 0.62
CYP1A1 P04798 5/20 0.62
CYP1B1 Q16678 5/20 0.62
P4HB P07237 1/20 0.60
HCAR2 Q8TDS4 2/20 0.59
CA12 O43570 1/20 0.59
AKR1B10 O60218 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
ESR1 P03372 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80571 1.00 CYP1A2 (0.75) CYP1A2HDAC3HDAC1HDAC2HDAC10
Hydrochloric Acid SCHEMBL6510827 0.98 CYP1A2 (0.72) CYP1A2HDAC3HDAC1HDAC2HDAC10
Hydrochloric Acid SCHEMBL27760116 0.98 CYP1A2 (0.72) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL6845616 0.91 CYP1A2 (0.64) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL6845622 0.91 CYP1A2 (0.64) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL6845615 0.91 CYP1A2 (0.64) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL10467114 0.89 CYP1A2 (0.83) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL10467116 0.89 CYP1A2 (0.83) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL30662308 0.88 HDAC3 (0.63) CYP1A2HDAC3HDAC1HDAC2HDAC10
SCHEMBL5572624 0.87 CYP1A2 (0.62) CYP1A2HDAC3HDAC1HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132052-A1 NANOPARTICLE, AND INK COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS AND ELECTRONIC DEVICE, INCLUDING THE NANOPARTICLE SAMSUNG DISPLAY CO LTD (KR) 2026-05-14 US claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US claimed
CN-119371372-A Bcr-Abl targeting molecular gel and preparation method and application thereof 中山大学 2025-01-28 CN claimed
US-20220259490-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2022-08-18 US claimed
CN-109896684-B Sewage pretreatment process in organic product preparation process 李德祥 2021-12-24 CN claimed
CN-112920133-A (E) -4-methyl-2- (4- (trifluoromethyl) styryl) oxazole compound and preparation method and application thereof 中国医科大学 2021-06-08 CN claimed
WO-2020252075-A1 LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-12-17 WO claimed
CN-111018735-A Preparation method of cinnamamide 河南农业大学 2020-04-17 CN claimed
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-01-28 US claimed
CN-109896684-A A kind of pre-treating process for sewage in organic products preparation process 李德祥 2019-06-18 CN claimed
EP-0990047-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES Rapigene, Inc. (US) 2000-04-05 EP claimed
US-6027890-A DETECTING LIGAND BINDING BY INCUBATING TAGGED MEMBERS WITH BIOLOGICAL SAMPLE, SEPARATING BOUND FROM UNBOUND MEMBERS, CLEAVING TAG, THEN DETECTING BY NON-FLUORESCENT SPECTROSCOPY OR POTENTIOMETRY RAPIGENE, INC. (US) 2000-02-22 US claimed
EP-0962464-A2 Methods and compositions for detecting binding of ligand pair using non-fluorescent label Rapigene, Inc. (US) 1999-12-08 EP claimed
WO-1999005319-A9 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE INC (US) 1999-06-17 WO claimed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO claimed
EP-0868535-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES Rapigene, Inc. (US) 1998-10-07 EP claimed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES 1997-10-09 WO claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
EP-0612734-A1 Novel orally active antifungal agents J. URIACH & CIA. S.A. (ES) 1994-08-31 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132052-A1 NANOPARTICLE, AND INK COMPOSITION, LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS AND ELECTRONIC DEVICE, INCLUDING THE NANOPARTICLE L1CAM, LASP1, CD63 CYP1A2 728/4885HDAC3 3946/4885HDAC1 2969/4885
US-10544168-B2 Ligand-exchangeable nanoparticles and methods of making the same CA6, CA13, EPCAM CYP1A2 432/4885HDAC3 2613/4885HDAC1 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.