SCHEMBL8057008

SCHEMBL8057008

C=CC(O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.60
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KDM4E B2RXH2 2/20 0.39
PDE4A P27815 1/20 0.39
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
TOP1 P11387 1/20 0.32
MGAM O43451 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28074939 1.00 TDP1 (0.60) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL17472887 1.00 TDP1 (0.60) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL16153910 0.97 LMNA (0.58) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL16153889 0.97 LMNA (0.58) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL14411837 0.97 LMNA (0.58) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL15698703 0.97 LMNA (0.58) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL7154884 0.90 LMNA (0.53) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL3089641 0.90 LMNA (0.53) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL9204113 0.90 LMNA (0.53) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL7155404 0.90 LMNA (0.53) TDP1LMNAL3MBTL1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127181-A PRECULTURING PLANT CELL WITH DIVALENT CATION AT GREATER THAN 5 MM AND OSMOTIC AGENT TO STABILIZE CELL MEMBRANES; THEN, IN ANY ORDER, APPLYING CRYOPROTECTANT, VITRIFYING WITH CRYOPROTECTANT SOLUTION, AND FREEZING CELLS PHYTON, INC. (US) 2000-10-03 US disclosed
US-5965438-A PRETREATING THE PLANT CELL WITH CRYOPROTECTIVE AGENT AND STABILIZER WHICH IS ANTIOXIDANT OR RADICAL SCAVENGER; THEN IN ANY ORDER, ACCLIMATING CELL TO REDUCED TEMPERATURE, LOADING CELL, VITRIFYING CELL, AND FREEZING TO DESIRED TEMPERATURE PHYTON, INC. (US) 1999-10-12 US disclosed
EP-0830059-A2 CRYOPRESERVATION OF DIVERSE PLANT CELLS PHYTON, INC. (US) 1998-03-25 EP disclosed
WO-1996039812-A2 CRYOPRESERVATION OF DIVERSE PLANT CELLS PHYTON, INC. (US) 1996-12-19 WO disclosed