SCHEMBL8057789

SCHEMBL8057789

CCCCCCCCCCCCN1CNC(=S)NC1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
GNAI3 P08754 6/20 0.41
GNAO1 P09471 6/20 0.41
GNAI1 P63096 6/20 0.41
GUSB P08236 2/20 0.40
EBP Q15125 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10630470 0.92 MAPT (0.57) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL10630257 0.89 MAPT (0.64) MAPTALDH1A1KMT2ATDP1
SCHEMBL10630436 0.83 MAPT (0.61) MAPTALDH1A1CYP2C19MEN1KMT2A
SCHEMBL10630265 0.83 MAPT (0.67) MAPTALDH1A1KMT2ATDP1
SCHEMBL10630523 0.78 MAPT (0.73) MAPTALDH1A1CYP1A2MEN1KMT2A
SCHEMBL10626251 0.75 MAPT (0.76) MAPTALDH1A1KMT2ATDP1
Hydrochloric Acid SCHEMBL27558043 0.73 GNAO1 (0.43) ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3
SCHEMBL8751413 0.72 GNAO1 (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3
SCHEMBL3313743 0.72 GNAO1 (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3
SCHEMBL3310643 0.72 GNAO1 (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0651063-B1 Improvements in or relating to the recovery of silver AGFA GEVAERT NV (BE) 2000-05-10 EP disclosed
EP-0651063-A1 Improvements in or relating to the recovery of silver Du Pont (UK) Limited (GB) 1995-05-03 EP disclosed