Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 5/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603890 | 1.00 | CA2 (0.36) | CA2BIRC2ZDHHC7MAPTMMP2 | |
| SCHEMBL8603892 | 1.00 | CA2 (0.36) | CA2BIRC2ZDHHC7MAPTMMP2 | |
| SCHEMBL29284587 | 0.80 | CA2 (0.51) | CA2BIRC2ZDHHC7MAPTGAA | |
| SCHEMBL6860015 | 0.80 | CA2 (0.46) | CA2BIRC2ATMCTSKCA1 | |
| SCHEMBL7069281 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 | |
| SCHEMBL7304504 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 | |
| SCHEMBL6138155 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 | |
| SCHEMBL8217020 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 | |
| SCHEMBL6808467 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 | |
| SCHEMBL8217023 | 0.77 | GRIK1 (0.50) | CA2BIRC2MAPTGAAGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | disclosed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | disclosed |