Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL8997978 | 0.87 | SLC7A11 (0.68) | SLC7A11KDM4EALDH1A1LMNASMN1; SMN2 | |
| Alcohol SCHEMBL8057903 | 0.87 | SLC7A11 (0.68) | SLC7A11KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8067259 | 0.85 | FASN (0.52) | SLC7A11ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8072369 | 0.79 | SLC7A11 (0.69) | SLC7A11KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8072366 | 0.79 | SLC7A11 (0.69) | SLC7A11KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8069398 | 0.78 | SLC7A11 (0.79) | SLC7A11KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL8069397 | 0.78 | SLC7A11 (0.79) | SLC7A11KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL27330492 | 0.74 | SLC7A11 (0.63) | SLC7A11ALDH1A1LMNASMN1; SMN2POLB | |
| Alcohol SCHEMBL8067256 | 0.74 | SLC7A11 (0.60) | SLC7A11ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL11965816 | 0.74 | CA12 (0.69) | KMT2APTGS2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613468-B1 | Substituted salicylic acids for the treatment of autoimmune diseases | PHARMACIA & UPJOHN AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| US-5556855-A | TREATMENT OF AUTOIMMUNE DISEASES | PHARMACIA AB (SE) | 1996-09-17 | — | — | US | disclosed |
| US-5403930-A | Chemical intermediate for drugs used in autoimmune diseases | PHARMACIA AB (SE) | 1995-04-04 | — | — | US | disclosed |
| US-5302718-A | Used for treating autoimmune diseases | KABI PHARMACIA AB (SE) | 1994-04-12 | — | — | US | disclosed |