Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27330492 | 0.89 | SLC7A11 (0.63) | FASNMAPTCYP2C9SLC7A11NPSR1 | |
| Alcohol SCHEMBL8067256 | 0.88 | SLC7A11 (0.60) | FASNRXFP1MAPTCYP2C9SLC7A11 | |
| SCHEMBL8057906 | 0.85 | SLC7A11 (0.56) | MAPTSLC7A11ALDH1A1LMNAPOLB | |
| SCHEMBL11965816 | 0.74 | CA12 (0.69) | KMT2A | |
| SCHEMBL8068575 | 0.74 | SLC7A11 (0.52) | MAPTSLC7A11NPSR1MAPK1ALDH1A1 | |
| SCHEMBL8068573 | 0.74 | SLC7A11 (0.52) | MAPTSLC7A11NPSR1MAPK1ALDH1A1 | |
| SCHEMBL8072366 | 0.74 | SLC7A11 (0.69) | RXFP1MAPTCYP2C9SLC7A11MAPK1 | |
| SCHEMBL8072369 | 0.74 | SLC7A11 (0.69) | RXFP1MAPTCYP2C9SLC7A11MAPK1 | |
| SCHEMBL9144877 | 0.73 | SLC7A11 (0.58) | MAPTSLC7A11POLBSMN1; SMN2MEN1 | |
| SCHEMBL9144880 | 0.73 | SLC7A11 (0.58) | MAPTSLC7A11POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613468-B1 | Substituted salicylic acids for the treatment of autoimmune diseases | PHARMACIA & UPJOHN AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| US-5556855-A | TREATMENT OF AUTOIMMUNE DISEASES | PHARMACIA AB (SE) | 1996-09-17 | — | — | US | disclosed |
| US-5403930-A | Chemical intermediate for drugs used in autoimmune diseases | PHARMACIA AB (SE) | 1995-04-04 | — | — | US | disclosed |
| US-5302718-A | Used for treating autoimmune diseases | KABI PHARMACIA AB (SE) | 1994-04-12 | — | — | US | disclosed |