Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058266 | 1.00 | PTPN1 (0.47) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL2951695 | 0.88 | ALDH1A1 (0.59) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL5013682 | 0.88 | ALDH1A1 (0.55) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL5009929 | 0.87 | ALDH1A1 (0.62) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL8060168 | 0.85 | ITGB1 (0.57) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL21690440 | 0.85 | KMT2A (0.58) | PTPN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21689918 | 0.85 | KMT2A (0.58) | PTPN1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2857963 | 0.85 | ITGB1 (0.57) | PTPN1SLC7A5ITGB3ITGA2BPTGS1 | |
| SCHEMBL27647466 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2ALMNA | |
| Dl-Phenylalanine SCHEMBL27693339 | 0.80 | ALPI (0.54) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999006390-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |