Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL24341 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1254633 | 0.88 | — | — | |
| Bicarbonate SCHEMBL11420335 | 0.88 | — | — | |
| Bicarbonate SCHEMBL5077399 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1903311 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL51090 | 0.88 | — | — | |
| Bicarbonate SCHEMBL2179586 | 0.88 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL290408 | 0.88 | — | — | |
| Bicarbonate SCHEMBL11685556 | 0.88 | — | — | |
| Bicarbonate SCHEMBL10394677 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153782-A | Method of producing propylsilanes | DEGUSSA-HULS AG (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0454022-B1 | Catalyst and process for dehydrogenation and dehydrocyclization | PHILLIPS PETROLEUM CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5143888-A | Dehydrogenation, dehydrocyclization | PHILLIPS PETROLEUM COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5073662-A | Zinc aluminate with calcium aluminate as catalyst support | PHILLIPS PETROLEUM COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0454022-A1 | Catalyst and process for dehydrogenation and dehydrocyclization | PHILLIPS PETROLEUM COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0166359-B1 | RECYCLE OF BUTADIENE PRODUCT IN CATALYTIC DEHYDROGENATION PROCESS | PHILLIPS PETROLEUM COMPANY (US) | 1990-08-01 | — | — | EP | disclosed |
| EP-0166359-A2 | Recycle of butadiene product in catalytic dehydrogenation process | PHILLIPS PETROLEUM COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4206035-A | CATALYTIC DEHYDROGENATION | PHILLIPS PETROLEUM COMPANY (US) | 1980-06-03 | — | — | US | disclosed |