Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776016 | 1.00 | CYP2A6 (0.36) | CYP2A6ALOX12ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL205284 | 1.00 | — | — | |
| SCHEMBL102781 | 0.81 | MEN1 (0.37) | ALDH1A1CYP3A4ALOX15SMN1; SMN2LMNA | |
| SCHEMBL709852 | 0.75 | MAPT (0.39) | ALDH1A1ALOX15LMNATSHRKDM4E | |
| SCHEMBL577541 | 0.73 | GAA (0.43) | ALOX12CYP3A4ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL11095966 | 0.73 | TSHR (0.43) | CYP2A6TSHRNPC1 | |
| SCHEMBL1750074 | 0.73 | MAOA (0.42) | CYP2A6ALDH1A1CYP3A4ALOX15SMN1; SMN2 | |
| SCHEMBL8912020 | 0.73 | TSHR (0.43) | CYP2A6TSHRNPC1 | |
| SCHEMBL229977 | 0.73 | BCHE (0.42) | ALOX12ALDH1A1CYP3A4ALOX15KDM4E | |
| SCHEMBL577542 | 0.73 | GAA (0.43) | ALOX12CYP3A4ALOX15SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359102-A | Having cyclopentadienyl, indenyl, dicyclopentadienyl, and or fluorenyl group or theier derivatives as a legand used together with cocatalyst aluminoxane | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-25 | — | — | US | claimed |
| EP-1012201-A1 | POLY(ARYL VINYLENE)S | White Knight Technologies Limited (GB) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999014255-A1 | POLY(ARYL VINYLENE)S | WHITE KNIGHT TECHNOLOGIES LIMITED (GB) | 1999-03-25 | — | — | WO | disclosed |
| EP-0528041-B1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5439994-A | Preparing polymers with wide molecular weight distribution | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5359102-A | Having cyclopentadienyl, indenyl, dicyclopentadienyl, and or fluorenyl group or theier derivatives as a legand used together with cocatalyst aluminoxane | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0528041-A1 | NOVEL TRANSITION METAL COMPOUND AND PROCESS FOR POLYMERIZING OLEFIN BY USING THE SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-24 | — | — | EP | disclosed |