Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157436 | 0.84 | HPGD (0.41) | GAAALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL6122746 | 0.83 | AR (0.34) | GAAKEAP1NFE2L2CYP3A4ALDH1A1 | |
| SCHEMBL3973298 | 0.83 | TSHR (0.39) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2821543 | 0.82 | TSHR (0.50) | GAAALDH1A1PKMLMNACA1 | |
| SCHEMBL156311 | 0.81 | MAPT (0.47) | CYP3A4ALDH1A1PKMLMNACA1 | |
| SCHEMBL18504886 | 0.79 | ALDH1A1 (0.47) | CYP3A4ALDH1A1PKMLMNAL3MBTL1 | |
| SCHEMBL22324638 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL17723416 | 0.70 | APOBEC3A (0.35) | GAAALDH1A1PKMLMNAMEN1 | |
| SCHEMBL13612949 | 0.69 | KDM4E (0.39) | GAAALDH1A1ALOX15LMNAMEN1 | |
| SCHEMBL3156748 | 0.68 | TDP1 (0.36) | ALDH1A1LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076352-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |