Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28193565 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBSMN1; SMN2KDM4EMAPT | |
| Quinoxaline SCHEMBL28142577 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoline SCHEMBL1562542 | 0.81 | ALDH1A1 (0.65) | ALDH1A1POLBSMN1; SMN2KDM4EMAPT | |
| Quinoxaline SCHEMBL28795554 | 0.80 | KDM4E (0.44) | ALDH1A1POLBPTK2KDM4EMAPT | |
| Quinoxaline SCHEMBL5315 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoxaline SCHEMBL29355228 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoxaline SCHEMBL6928518 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoxaline SCHEMBL30320908 | 0.79 | ALDH1A1 (0.58) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoxaline SCHEMBL2431603 | 0.76 | ALDH1A1 (0.55) | ALDH1A1POLBKDM4EMAPTLMNA | |
| Quinoxaline SCHEMBL5358841 | 0.76 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936967-B | Containing thiadiazoles quinoxaline unit Naphthalenetetracarbacidic acidic diimide copolymer and its preparation method and application | 海洋王照明科技股份有限公司 | 2016-09-07 | — | — | CN | disclosed |
| US-6057077-A | Method for producing a positive or negative color-proof using the same materials | AGFA-GEVAERT N.V. (BE) | 2000-05-02 | — | — | US | disclosed |