SCHEMBL8058762

SCHEMBL8058762

C=CNc1ccccc1.O=S(=O)(O)C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
PKM P14618 1/20 0.42
HTT P42858 1/20 0.41
LMNA P02545 3/20 0.40
PPARG P37231 3/20 0.40
MAOB P27338 2/20 0.40
EGFR P00533 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MAOA P21397 1/20 0.40
NFE2L2 Q16236 1/20 0.40
ALDH1A1 P00352 3/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSP90AA1 P07900 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vinylsulfonic Acid SCHEMBL4370936 0.83 PPARG (0.47) KMT2APKMHTTLMNAPPARG
Butadiene SCHEMBL1469580 0.83 PPARG (0.47) KMT2APKMHTTLMNAPPARG
SCHEMBL28217339 0.83 PPARG (0.47) KMT2APKMHTTLMNAPPARG
Vinylsulfonic Acid SCHEMBL8060920 0.83 ALDH1A1 (0.45) PKMALDH1A1GAAKDM4EPOLB
Formaldehyde SCHEMBL10338470 0.82 PPARG (0.50) KMT2APKMHTTLMNAPPARG
Ethylene SCHEMBL131455 0.82 PPARG (0.50) KMT2APKMHTTLMNAPPARG
SCHEMBL15001 0.82 PPARG (0.53) KMT2APKMHTTLMNAPPARG
SCHEMBL1201904 0.82 PPARG (0.53) KMT2APKMHTTLMNAPPARG
SCHEMBL2496181 0.82 PPARG (0.53) KMT2APKMHTTLMNAPPARG
Ethylene SCHEMBL2221318 0.81 PPARG (0.46) KMT2APKMHTTLMNAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1136951-C Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use �ƿ˱�Ĥϵͳ��˾ 2004-02-04 CN claimed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed
CN-1207956-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS INC (US) 1999-02-17 CN claimed
EP-0884096-A1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use Crosswinds, Inc. (US) 1998-12-16 EP claimed
US-4584103-A REACTING WITH HYDROXYLAMINE, THEN DIFUNCTIONAL COMPOUND AND COMPOUND CONTAINING IONIZABLE GROUP ALIGENA AG (CH) 1986-04-22 US disclosed