Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805962 | 0.87 | SCN9A (0.58) | SCN9AS1PR2ENPP2 | |
| SCHEMBL805870 | 0.86 | SCN9A (0.65) | SCN9AS1PR2ENPP2GRIA1 | |
| SCHEMBL15383835 | 0.85 | SCN9A (0.73) | SCN9A | |
| SCHEMBL805965 | 0.84 | SCN9A (0.70) | SCN9AS1PR2 | |
| SCHEMBL805889 | 0.84 | SCN9A (0.77) | SCN9A | |
| SCHEMBL805897 | 0.84 | SCN9A (0.55) | SCN9AS1PR2ENPP2GRIA1 | |
| SCHEMBL18031540 | 0.81 | SCN9A (0.56) | SCN9AENPP2GRIA1LMNAMAPT | |
| SCHEMBL17049605 | 0.75 | SCN9A (0.54) | SCN9AS1PR2 | |
| SCHEMBL17049606 | 0.74 | SCN9A (0.52) | SCN9AS1PR2 | |
| SCHEMBL941160 | 0.74 | ALDH1A1 (0.62) | LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035421-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-03-22 | — | — | WO | disclosed |