Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061486 | 0.86 | PTPN1 (0.42) | PTPN1GLACETPALDH1A1PIN1 | |
| SCHEMBL5059816 | 0.85 | PTPN1 (0.41) | PTPN1CETPPIN1POLBSMN1; SMN2 | |
| SCHEMBL8046802 | 0.80 | ACP3 (0.39) | CETPALDH1A1PPARGMEN1KMT2A | |
| SCHEMBL7611446 | 0.80 | PTPN1 (0.45) | PTPN1CETPPIN1PPARGGAA | |
| SCHEMBL7611836 | 0.78 | PTPN1 (0.46) | PTPN1CETPPIN1PPARGMEN1 | |
| SCHEMBL7604569 | 0.77 | PTPN1 (0.47) | PTPN1CETPPIN1PPARGGAA | |
| SCHEMBL7605932 | 0.77 | PTPN1 (0.52) | PTPN1CETP | |
| SCHEMBL8046123 | 0.76 | PTPN1 (0.41) | PTPN1GLAALDH1A1PIN1PPARG | |
| SCHEMBL7610346 | 0.76 | PTPN1 (0.43) | PTPN1CETPPIN1PPARGMEN1 | |
| SCHEMBL7610316 | 0.74 | CETP (0.45) | PTPN1CETPPPARGSMN1; SMN2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |