Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917893 | 0.85 | NAAA (0.42) | NAAAALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL16838363 | 0.85 | NAAA (0.41) | NAAACYP2C19CYP19A1 | |
| SCHEMBL8690677 | 0.84 | — | — | |
| SCHEMBL28869002 | 0.84 | NAAA (0.49) | NAAAALDH1A1CYP2C19CYP19A1NLRP3 | |
| SCHEMBL21555532 | 0.83 | NAAA (0.45) | NAAAALDH1A1CYP2C19CYP19A1NLRP3 | |
| SCHEMBL16837528 | 0.81 | NAAA (0.46) | NAAAALDH1A1CYP2C19CYP19A1NLRP3 | |
| SCHEMBL1695592 | 0.80 | NAAA (0.72) | NAAAALDH1A1CYP2C19CYP19A1SMN1; SMN2 | |
| SCHEMBL2433610 | 0.80 | NAAA (0.67) | NAAAALDH1A1CYP2C19CYP19A1SMN1; SMN2 | |
| SCHEMBL28208008 | 0.80 | NAAA (0.49) | NAAAALDH1A1CYP2C19CYP19A1NLRP3 | |
| SCHEMBL27616995 | 0.79 | CYP2C19 (0.40) | NAAACYP2C19CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112969444-A | Use of 1-ethyl-4, 4-dimethylcyclohexane derivatives as fragrance substances | 西姆莱斯有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-112969444-A | Use of 1-ethyl-4, 4-dimethylcyclohexane derivatives as fragrance substances | 西姆莱斯有限公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-112969444-A | Use of 1-ethyl-4, 4-dimethylcyclohexane derivatives as fragrance substances | 西姆莱斯有限公司 | 2021-06-15 | — | — | CN | disclosed |
| EP-2861601-B1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | GILEAD SCIENCES INC (US) | 2018-02-07 | — | — | EP | disclosed |
| US-20170190734-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | Selcia Ltd. (GB) | 2017-07-06 | — | — | US | disclosed |
| US-9642889-B2 | Macrocyclic inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160220633-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | CYPRALIS LIMITED (GB) | 2016-08-04 | — | — | US | disclosed |
| US-20150361132-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | CYPRALIS LIMITED (GB) | 2015-12-17 | — | — | US | disclosed |
| US-9062092-B2 | Macrocyclic inhibitors of Flaviviridae viruses | GILEAD SCIENCES, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-6025323-A | CONFERRING AROMATIC AND THUJONIC NOTES TO PERFUMES | FIRMENICH SA (CH) | 2000-02-15 | — | — | US | disclosed |
| EP-0868502-B1 | USE OF CYCLIC KETONES IN PERFUMERY | FIRMENICH & CIE (CH) | 1999-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220633-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | HAVCR2, ZC3HAV1, HCCS | NAAA 2162/4885ALDH1A1 1076/4885CYP2C19 71/4885 |
| US-20170190734-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | HAVCR2, ZC3HAV1, HCCS | NAAA 2162/4885ALDH1A1 1076/4885CYP2C19 71/4885 |
| US-20150361132-A1 | MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES | HAVCR2, ZC3HAV1, HCCS | NAAA 2162/4885ALDH1A1 1076/4885CYP2C19 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.