Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059374 | 1.00 | CYP2C9 (0.51) | CYP2C9CYP2C19RAB9ASMN1; SMN2GAA | |
| SCHEMBL30437445 | 0.86 | ELANE (0.50) | CYP2C9CYP2C19RAB9ASMN1; SMN2GAA | |
| SCHEMBL3513496 | 0.84 | RAB9A (0.50) | CYP2C19RAB9ASMN1; SMN2GAAMEN1 | |
| SCHEMBL3510637 | 0.84 | RAB9A (0.50) | CYP2C19RAB9ASMN1; SMN2GAAMEN1 | |
| SCHEMBL5274809 | 0.83 | CYP2C9 (0.52) | CYP2C9CYP2C19SMN1; SMN2GAAMEN1 | |
| SCHEMBL5274814 | 0.83 | CYP2C9 (0.52) | CYP2C9CYP2C19SMN1; SMN2GAAMEN1 | |
| SCHEMBL5342235 | 0.81 | RAB9A (0.50) | CYP2C9CYP2C19RAB9ASMN1; SMN2GAA | |
| SCHEMBL5377321 | 0.81 | RAB9A (0.50) | CYP2C9CYP2C19RAB9ASMN1; SMN2GAA | |
| SCHEMBL5342232 | 0.81 | RAB9A (0.50) | CYP2C9CYP2C19RAB9ASMN1; SMN2GAA | |
| SCHEMBL27796172 | 0.80 | RAB9A (0.52) | RAB9ASMN1; SMN2KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080588-A | ADMINISTERING DERIVATIVE TO SUBJECT TO INHIBIT OR PREVENT DISEASE ASSOCIATED WITH BINDING OF ANTIBODIES TO DNA; TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND INFLAMMATORY GLOMERULONEPHRITIS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-06-27 | — | — | US | disclosed |
| WO-1996036361-A1 | DNA BINDING ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-11-21 | — | — | WO | disclosed |