Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.67 |
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675173 | 1.00 | STS (0.67) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL8154128 | 1.00 | STS (0.67) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL5679656 | 0.94 | STS (0.60) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL8151594 | 0.90 | STS (0.64) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL5678711 | 0.90 | STS (0.64) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL8151812 | 0.90 | STS (0.64) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL8145325 | 0.84 | STS (0.50) | STSHRH3KCNH2KDM4EALDH1A1 | |
| SCHEMBL14252903 | 0.84 | STS (0.70) | STSSHBGHRH3KCNH2KDM4E | |
| SCHEMBL8145247 | 0.83 | HRH3 (0.71) | STSSHBGHRH3KCNH2 | |
| SCHEMBL8144474 | 0.83 | HRH3 (0.77) | STSSHBGHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | claimed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | claimed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | disclosed |
| US-6046186-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | SRI INTERNATIONAL (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |