Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | STS | P08842 | 1/20 | 0.61 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144474 | 0.96 | HRH3 (0.77) | HRH3KCNH2STSSHBG | |
| SCHEMBL8144798 | 0.92 | HRH3 (0.63) | HRH3KCNH2STSSHBG | |
| SCHEMBL8152987 | 0.85 | HRH3 (0.68) | HRH3KCNH2STSSHBG | |
| SCHEMBL8154128 | 0.83 | STS (0.67) | HRH3KCNH2STSSHBG | |
| SCHEMBL5675173 | 0.83 | STS (0.67) | HRH3KCNH2STSSHBG | |
| SCHEMBL8059548 | 0.83 | STS (0.67) | HRH3KCNH2STSSHBG | |
| SCHEMBL14252903 | 0.82 | STS (0.70) | HRH3KCNH2STSSHBG | |
| SCHEMBL8151812 | 0.82 | STS (0.64) | HRH3KCNH2STSSHBG | |
| SCHEMBL5678711 | 0.82 | STS (0.64) | HRH3KCNH2STSSHBG | |
| SCHEMBL8151594 | 0.82 | STS (0.64) | HRH3KCNH2STSSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | claimed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | claimed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | disclosed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |