SCHEMBL805958

SCHEMBL805958

N#Cc1cccc[n+]1[O-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31536953 1.00
SCHEMBL10528992 0.76
SCHEMBL3997952 0.76
SCHEMBL28990980 0.76
SCHEMBL6594899 0.73 LMNA (0.45)
SCHEMBL8988114 0.71 HDAC8 (1.00)
SCHEMBL316876 0.71 SLC22A2 (0.38)
Iodide SCHEMBL30133746 0.70 HDAC8 (0.95)
Hydrochloric Acid SCHEMBL5833068 0.70 HDAC8 (0.95)
SCHEMBL16470114 0.68 HDAC8 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 WO claimed
EP-0901517-B1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS JOHNSON & SON INC S C (US) 2000-08-09 EP claimed
EP-0901517-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1999-03-17 EP claimed
US-5739096-A BLEACHING SYSTEM COMPRISING SURFACTANT, PEROXIDE, CYANOPYRIDINE N-OXIDE BLEACH ACTIVATOR S. C. JOHNSON & SON, INC. (US) 1998-04-14 US claimed
WO-1997042295-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1997-11-13 WO claimed
US-12528816-B2 Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors CARDURION PHARMACEUTICALS, INC. (US) 2026-01-20 US disclosed
US-20240182474-A1 SUBSTITUTED IMIDAZO [1,2-b] PYRIDAZINES AND [1, 2, 4] TRIAZOLO [ 4,3-b] PYRIDAZINES AS CAMKII INHIBITORS CARDURION PHARMACEUTICALS, INC. 2024-06-06 US disclosed
US-11795172-B2 Substituted imidazo[1,2-b]pyridazines and [1,2,4]triazolo[4,3-b]pyridazines as CaMKII inhibitors CARDURION PHARMACEUTICALS, INC. (US) 2023-10-24 US disclosed
US-20220098207-A1 FUSED HETEROARYL COMPOUNDS AND THEIR USE AS CAMKII INHIBITORS CARDURION PHARMACEUTICALS, INC. 2022-03-31 US disclosed
US-9611222-B2 Pyridine compounds and the uses thereof PURDUE PHARMA L.P. (US) 2017-04-04 US disclosed
CN-104411686-B Process for producing 4- [5- (pyridin-4-yl) -1H-1,2, 4-triazol-3-yl ] pyridine-2-carbonitrile and intermediate 株式会社富士药品 2016-08-31 CN disclosed
US-20150259293-A1 PYRIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA L.P. 2015-09-17 US disclosed
EP-0901517-B1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS JOHNSON & SON INC S C (US) 2000-08-09 EP disclosed
EP-0901517-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1999-03-17 EP disclosed
EP-0901517-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1999-03-17 EP disclosed
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed
US-5739096-A BLEACHING SYSTEM COMPRISING SURFACTANT, PEROXIDE, CYANOPYRIDINE N-OXIDE BLEACH ACTIVATOR S. C. JOHNSON & SON, INC. (US) 1998-04-14 US disclosed
US-5739096-A BLEACHING SYSTEM COMPRISING SURFACTANT, PEROXIDE, CYANOPYRIDINE N-OXIDE BLEACH ACTIVATOR S. C. JOHNSON & SON, INC. (US) 1998-04-14 US disclosed
WO-1997042295-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1997-11-13 WO disclosed
WO-1997042295-A1 CYANOPYRIDINE N-OXIDE PEROXIDE BLEACH ACTIVATORS S.C. JOHNSON & SON, INC. (US) 1997-11-13 WO disclosed