SCHEMBL8059644

SCHEMBL8059644

O=C=NC1=C(Cl)CCCC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333543 0.82 CYP3A4 (0.33)
SCHEMBL8425533 0.76
SCHEMBL8059746 0.71 CYP3A4 (0.32)
SCHEMBL10679809 0.70 CYP3A4 (0.31)
SCHEMBL10939963 0.70 CYP3A4 (0.35)
SCHEMBL8053397 0.67
SCHEMBL7867592 0.66
SCHEMBL31087640 0.64 LMNA (0.39)
SCHEMBL2464072 0.64
SCHEMBL10712112 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728750-B1 1-Cycloalkenyltetrazolinones BAYER AGROCHEM KK (JP) 2000-05-17 EP disclosed
US-5654257-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1997-08-05 US disclosed
EP-0728750-A1 1-Cycloalkenyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-08-28 EP disclosed