Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.62 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284138 | 0.85 | SCN9A (0.59) | SCN9A | |
| SCHEMBL805954 | 0.85 | SCN9A (0.69) | SCN9A | |
| SCHEMBL805973 | 0.82 | SCN9A (0.61) | SCN9A | |
| SCHEMBL806018 | 0.79 | SCN9A (0.68) | SCN9A | |
| SCHEMBL787484 | 0.77 | SCN9A (1.00) | SCN9A | |
| SCHEMBL21236833 | 0.75 | SCN9A (0.62) | SCN9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL805907 | 0.74 | SCN9A (0.65) | SCN9ALMNA | |
| SCHEMBL9256336 | 0.73 | IRAK4 (0.49) | SCN9A | |
| SCHEMBL10284267 | 0.72 | SCN9A (0.67) | SCN9AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL805975 | 0.70 | SCN9A (0.55) | SCN9AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035421-A2 | PYRIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-03-22 | — | — | WO | disclosed |