Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061868 | 0.94 | CMA1 (0.78) | CMA1CTSG | |
| SCHEMBL8060664 | 0.92 | CMA1 (0.70) | CMA1CTSG | |
| SCHEMBL8059717 | 0.91 | CMA1 (0.68) | CMA1CTSG | |
| SCHEMBL8060533 | 0.88 | CMA1 (0.86) | CMA1CTSG | |
| SCHEMBL8064213 | 0.86 | CMA1 (0.78) | CMA1CTSG | |
| SCHEMBL7156029 | 0.86 | CMA1 (0.78) | CMA1CTSG | |
| SCHEMBL8061333 | 0.85 | CMA1 (0.74) | CMA1CTSG | |
| SCHEMBL8066009 | 0.85 | CMA1 (0.68) | CMA1CTSG | |
| SCHEMBL8445442 | 0.84 | CMA1 (0.64) | CMA1 | |
| SCHEMBL8444748 | 0.82 | CMA1 (0.78) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080738-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE USED FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II | YOSHITOMI PHARMACEUTICALS INDUSTRIES, LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0940400-A1 | NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USES THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-08 | — | — | EP | disclosed |