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Sugi Predict / Compounds / SCHEMBL8445442

SCHEMBL8445442

SCHEMBL8445442

Cc1cccc(-c2ncc(NC(=O)OCc3ccccc3)c(=O)n2CC(=O)NC(Cc2ccccc2)C(=O)c2nc3ncccc3o2)c1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CMA1 P23946 10/20 0.64
▸ ELANE P08246 10/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8066152 0.96 CMA1 (0.68) CMA1ELANE
SCHEMBL8060635 0.94 CMA1 (0.63) CMA1ELANE
SCHEMBL8059788 0.86 CMA1 (0.84) CMA1
SCHEMBL8060664 0.85 CMA1 (0.70) CMA1
SCHEMBL8059783 0.84 CMA1 (0.68) CMA1
SCHEMBL8049020 0.84 CMA1 (0.75) CMA1ELANE
SCHEMBL8059717 0.83 CMA1 (0.68) CMA1
SCHEMBL8059799 0.82 CMA1 (0.91) CMA1
SCHEMBL8064213 0.81 CMA1 (0.78) CMA1
SCHEMBL6558274 0.80 ELANE (0.77) CMA1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0940400-A1 NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USES THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-09-08 — — EP disclosed