Dl-Tryptophan

Dl-Tryptophan

SCHEMBL8059982

NC(CCC(=O)O)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.82
MAPT P10636 3/20 0.82
KMT2A Q03164 3/20 0.82
LMNA P02545 2/20 0.82
TSHR P16473 2/20 0.82
BLM P54132 2/20 0.82
PMP22 Q01453 2/20 0.82
MEN1 O00255 2/20 0.82
MPO P05164 1/20 0.82
HIF1A Q16665 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.59
APAF1 O14727 1/20 0.58
POLB P06746 1/20 0.58
RECQL P46063 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HTR2A P28223 3/20 0.57
HTR1A P08908 2/20 0.57
HTR2C P28335 2/20 0.57
SLC6A4 P31645 2/20 0.57
HTR7 P34969 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL27153460 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL6688035 1.00 KDM4E (0.82) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL1458870 0.95 KMT2A (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL22500891 0.95 KMT2A (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28003348 0.94 KDM4E (0.73) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27865136 0.94 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL1487572 0.94 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27522281 0.93 KDM4E (0.89) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL7855013 0.92 KDM4E (0.70) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL22500851 0.92 KDM4E (0.70) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117599013-A Nanometer composition, preparation method and application thereof 赣州和美药业股份有限公司 2024-02-27 CN claimed
CN-110777123-B Mutant L-amino acid ligase and process for preparing L-glutamic acid-L-tryptophan dipeptide by enzyme catalysis method 深圳瑞德林生物技术有限公司 2021-05-18 CN claimed
CN-117599013-A Nanometer composition, preparation method and application thereof 赣州和美药业股份有限公司 2024-02-27 CN disclosed
US-20230064644-A1 Compositions and Methods for Controlling Production of Polypeptides in Cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-03-02 US disclosed
CN-115368436-A Peptidyl platinum self-assembly nano prodrug and preparation method and application thereof 南开大学 2022-11-22 CN disclosed
WO-2021158651-A9 COMPOSITIONS AND METHODS FOR CONTROLLING PRODUCTION OF POLYPEPTIDES IN CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2021-11-11 WO disclosed
WO-2021158651-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PRODUCTION OF POLYPEPTIDES IN CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2021-08-12 WO disclosed
CN-106333922-B Dipeptide hydrogel, preparation method and application thereof 中国科学院过程工程研究所 2020-08-11 CN disclosed
US-6051570-A ANTIULCER AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-04-18 US disclosed
EP-0983263-A1 NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-03-08 EP disclosed
WO-1998054172-A1 NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S RESEARCH FOUNDATION (IN) 1998-12-03 WO disclosed