Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | MPO | P05164 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL22500891 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL27868840 | 0.97 | KMT2A (0.70) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL27153460 | 0.95 | KDM4E (0.82) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL6688035 | 0.95 | KDM4E (0.82) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL8059982 | 0.95 | KDM4E (0.82) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL4654771 | 0.92 | KMT2A (0.73) | KMT2AKDM4EMAPTMEN1LMNA | |
| D-Tryptophan SCHEMBL11869971 | 0.92 | KMT2A (0.89) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL120930 | 0.92 | KMT2A (0.89) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL27641165 | 0.92 | KMT2A (0.89) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL120929 | 0.92 | KMT2A (0.89) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470216-A1 | PEPTIDE CLEARING AGENTS | Mologic Ltd (GB) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011036457-A1 | PEPTIDE CLEARING AGENTS | MOLOGIC LTD (GB) | 2011-03-31 | — | — | WO | disclosed |
| EP-1667702-A2 | PEPTIDES THAT INHIBIT COMPLEMENT ACTIVATION | Baxter International Inc., Baxter Healthcare Corp. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005023866-A2 | PEPTIDES THAT INHIBIT COMPLEMENT ACTIVATION | BAXTER INTERNATIONAL INC. (US) | 2005-03-17 | — | — | WO | disclosed |