Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | CASP7 | P55210 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799407 | 1.00 | IGLV6-57 (0.40) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7799210 | 1.00 | IGLV6-57 (0.40) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7803356 | 0.92 | AR (0.39) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7799196 | 0.92 | AR (0.39) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7801109 | 0.92 | AR (0.39) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7799406 | 0.92 | IGLV6-57 (0.45) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7799213 | 0.92 | IGLV6-57 (0.45) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7799208 | 0.92 | IGLV6-57 (0.45) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7803351 | 0.91 | ALDH1A1 (0.37) | IGLV6-57ARMAOBALDH1A1HPGD | |
| SCHEMBL7793602 | 0.91 | ALDH1A1 (0.37) | IGLV6-57ARMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156914-A | Donor-substituted oxindigo derivatives and their use as colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0900255-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | Ciba SC Holding AG (CH) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041176-A1 | DONOR-SUBSTITUTED OXINDIGO DERIVATIVES AND THEIR USE AS COLOURANTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-11-06 | — | — | WO | disclosed |