Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046411 | 1.00 | MAPT (0.40) | MAPTFAAHLMNAALDH1A1KDM4E | |
| SCHEMBL10069691 | 0.82 | FAAH (0.35) | MAPTFAAHLMNAALDH1A1MEN1 | |
| SCHEMBL10046538 | 0.78 | MAPT (0.37) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL18826093 | 0.77 | MAPT (0.36) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL18826095 | 0.77 | MAPT (0.36) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL18826091 | 0.77 | MAPT (0.36) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL17560015 | 0.76 | MAPT (0.40) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL10046362 | 0.75 | MAPT (0.36) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10046328 | 0.75 | MAPT (0.36) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL3320520 | 0.74 | FAAH (0.65) | MAPTFAAHALDH1A1GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037475-A1 | NOVEL COMPOSITIONS AND METHODS | CHEMSMART, LLC (US) | 2012-03-22 | — | — | WO | disclosed |