SCHEMBL8060359

SCHEMBL8060359

CCCCCc1ccc(C(=O)NO)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.70
HDAC8 Q9BY41 2/20 0.67
PLK1 P53350 1/20 0.67
HDAC3 O15379 2/20 0.60
HDAC2 Q92769 2/20 0.60
HDAC6 Q9UBN7 2/20 0.60
HDAC4 P56524 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
RARB P10826 5/20 0.60
SMPD1 P17405 2/20 0.60
NCOR2 Q9Y618 1/20 0.60
THRA P10827 2/20 0.58
THRB P10828 2/20 0.58
MEN1 O00255 1/20 0.58
ALDH1A1 P00352 1/20 0.58
RARA P10276 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504756 0.98 HDAC1 (0.73) HDAC1HDAC8PLK1HDAC3HDAC2
SCHEMBL6919330 0.95 PLK1 (0.74) HDAC1HDAC8PLK1HDAC3HDAC2
SCHEMBL4185605 0.94 RARB (0.69) HDAC1HDAC8PLK1RARBSMPD1
Acetic Acid SCHEMBL9504786 0.94 HDAC1 (0.71) HDAC1HDAC8PLK1RARBSMPD1
Acetic Acid SCHEMBL9504741 0.94 HDAC1 (0.71) HDAC1HDAC8PLK1RARBSMPD1
SCHEMBL21628550 0.91 HDAC1 (0.59) HDAC1HDAC8PLK1HDAC3HDAC2
SCHEMBL21628684 0.89 HDAC1 (0.61) HDAC1HDAC8PLK1RARBSMPD1
SCHEMBL6918978 0.87 PLK1 (0.72) HDAC1HDAC8PLK1HDAC3HDAC2
SCHEMBL2747801 0.86 PLK1 (0.67) PLK1RARBTHRATHRBMEN1
SCHEMBL21628407 0.85 PLK1 (0.62) HDAC1HDAC8PLK1HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119040670-A Gallium extraction agent, preparation method thereof and gallium extraction method 矿冶科技集团有限公司 2024-11-29 CN disclosed
CN-112745245-A Synthetic method of aryl hydroximic acid collecting agent 广东省科学院资源综合利用研究所 2021-05-04 CN disclosed
WO-2013059582-A2 SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES NUPOTENTIAL, INC. (US) 2013-04-25 WO disclosed
EP-0852028-B1 BLACK-AND-WHITE PHOTOTHERMOGRAPHIC AND THERMOGRAPHIC ELEMENTS COMPRISING HYDROXAMIC ACID COMPOUNDS AS CONTRAST ENHANCERS EASTMAN KODAK CO (US) 2000-06-07 EP disclosed
EP-0852028-A1 BLACK-AND-WHITE PHOTOTHERMOGRAPHIC AND THERMOGRAPHIC ELEMENTS COMPRISING HYDROXAMIC ACID COMPOUNDS AS CONTRAST ENHANCERS Imation Corp. (US) 1998-07-08 EP disclosed
WO-1997011410-A1 BLACK-AND-WHITE PHOTOTHERMOGRAPHIC AND THERMOGRAPHIC ELEMENTS COMPRISING HYDROXAMIC ACID COMPOUNDS AS CONTRAST ENHANCERS IMATION CORP. (US) 1997-03-27 WO disclosed
US-5545507-A ULTRAHIGH CONTRAST, RESOLUTION, SHARPNESS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-13 US disclosed