Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046538 | 0.90 | MAPT (0.37) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10046328 | 0.84 | MAPT (0.36) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10046362 | 0.84 | MAPT (0.36) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL17560015 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL18826093 | 0.79 | MAPT (0.36) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL18826095 | 0.79 | MAPT (0.36) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL18826091 | 0.79 | MAPT (0.36) | MAPTMEN1KMT2AATML3MBTL1 | |
| SCHEMBL29166710 | 0.77 | CA1 (0.40) | MAPTLMNAKDM4EDUSP3 | |
| SCHEMBL805998 | 0.77 | FAAH (0.42) | MAPT | |
| SCHEMBL10824905 | 0.75 | MAPT (0.40) | MAPTMEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037475-A1 | NOVEL COMPOSITIONS AND METHODS | CHEMSMART, LLC (US) | 2012-03-22 | — | — | WO | disclosed |